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Indications

ENBREL is indicated for reducing signs and symptoms, keeping joint damage from getting worse, and improving physical function in patients with moderately to severely active rheumatoid arthritis. ENBREL can be taken with methotrexate or used alone. Read More

ENBREL is indicated for chronic moderate to severe plaque psoriasis (PsO) in children 4 years and older and adults who may benefit from taking injections or pills (systemic therapy) or phototherapy (ultraviolet light). 
ENBREL is indicated for reducing signs and symptoms, keeping joint damage from getting worse, and improving physical function in patients with psoriatic arthritis. ENBREL can be used with or without methotrexate.
ENBREL is indicated for reducing signs and symptoms in patients with active ankylosing spondylitis. 
ENBREL is indicated for reducing signs and symptoms of moderately to severely active polyarticular juvenile idiopathic arthritis (JIA) in children ages 2 years and older. Close

ENBREL Support® Enrollment

You're now enrolled in ENBREL Support®.
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Welcome Specialists are available from 8:00 AM - 11:00 PM (ET), 7 days a week.

Save ENBREL Support® to your contacts so you know when ENBREL Support® is calling.

Welcome Specialists are available from 8:00 AM - 11:00 PM (ET), 7 days a week.

Add us to your contacts

Now that you have been prescribed ENBREL, your next step is to enroll in ENBREL Support®. All of the services and resources available to you through ENBREL Support® are designed to help patients like you start and stay on your new ENBREL treatment as prescribed.

ENBREL Support® enrollment is an easy way to sign up for resources that can help you establish and maintain your ENBREL treatment routine.

Ready to get started?

For which condition did your doctor prescribe ENBREL?

Sorry, you must have an ENBREL prescription to enroll. Talk to your doctor to see if ENBREL is right for you.

There are just 3 easy steps to select the resources and services that are best for you.

Let’s start by looking at resources to help pay for ENBREL

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Options for Paying for ENBREL

One of the first questions people ask is, “How much does ENBREL cost?” That’s why our financial resource specialists are there to make sure you’ve got the right information and the right kind of support based on your insurance status. Start by answering the following questions.

What best describes the type of prescription insurance you have?

The Enbrel® Co-Pay Card can help reduce out-of-pocket costs for eligible commercially insured patients.

Are you eligible for Medicare but receive prescription drug coverage from a former employer, union, or welfare plan?

By checking this box, I agree that I read, understand, and accept the Terms and Conditions of the Enbrel® Co-Pay Card.

Our team of Medicare Solutions Specialists know about Medicare and can help you understand your Medicare coverage, including the donut hole and anticipating annual out-of-pocket costs for ENBREL. We can also help you find answers to other questions you may have about ENBREL and your Medicare Part D or Medicaid plan, and more.

Their contact information will be provided after your enrollment is complete.

The Amgen Safety Net Foundation is an independent, nonprofit patient assistance program that helps patients with financial need gain access to ENBREL at no cost.

Their contact information will be provided after your enrollment is complete.

Our team of Insurance Specialists may be able to help you figure out how to lower your out-of-pocket costs for ENBREL.

Their contact information will be provided after your enrollment is complete.

I’m not interested in financial options.

The next step is selecting your injection device and starting a treatment routine.

You must complete all required information above to proceed.
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Establishing Your Treatment Routine

Once you start treatment after your healthcare provider has trained you on how to inject and reviewed the Instructions for Use, it’s important to get into a consistent routine for administering your ENBREL medication. ENBREL has a number of resources to help you establish a good routine, including supplemental injection demo videos and one-on-one assistance from ENBREL Nurse Partners™.

To get started, please select which device you’ll use to inject your ENBREL medication.

ENBREL Nurse Partners

For additional assistance with establishing your ENBREL treatment routine, turn to one of our ENBREL Nurse Partners™, who can provide one-on-one support to help. ENBREL Nurse Partners™ can provide you help at home, by phone, email, or video chat. ENBREL Nurse Partners™ are nurses by training, but they are not part of your treatment team or an extension of your doctor’s office. ENBREL Nurse Partners™ do not inject patients with ENBREL. You will be referred to your doctor’s office for clinical advice.

Would you like to register for the ENBREL Nurse Partners™ program?

You’re just about done! There are a few more resources for your consideration that may also be helpful.

You must complete all required information above to proceed.

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Additional Resources

Whether you’re a new or experienced ENBREL patient or caregiver, we have an array of resources that can help you throughout your journey.


My Enbrel Guide

My ENBREL Guide

With the help of patients just like you, ENBREL Support® has created this clear, step-by-step guide to help you successfully get started on ENBREL.

You will receive a copy of My ENBREL Guide by mail within 3-5 business days. You will also receive a link to download when you complete your ENBREL Support® enrollment.

My ENBREL Guide has been added to your resources.


Statwise Symptom Tracker

STATWISE™ Symptom Tracker

When your doctor asks how you are doing on treatment, don’t just tell them how you’re feeling. Show them how you’re doing by tracking your symptoms.

One way to do this is with STATWISE™—a text message–based program that helps you track your joint pain, stiffness, and swelling each day, with a simple text message. Every 2 weeks, you’ll get a report in the mail to share with your doctor at your next appointment.

Is your mobile phone a smartphone? (eg, iPhone or Android phone)

Please make a selection

Day of the week you will take your prescribed ENBREL injection

Day of the week is required

You’re almost done. The last step is to provide your personal information and complete your ENBREL Support® Enrollment.

You must complete all required information above to proceed.

ENBREL Support® Enrollment

ENBREL Support® is ready to get you started with—and help you stay on—the treatment plan you’ve made with your doctor.

Following are the resources and services you have selected:

  • My ENBREL Guide
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    Add Back
  • STATWISE™ Symptom Tracker
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Patient Information

All information is required unless otherwise noted.

State is required
Date of birth is required
We're sorry—you must be 18 years or older to enroll. Please call ENBREL Support® to complete enrollment.

If you or your loved one is under 18 years of age, please call ENBREL Support® to complete enrollment.

Gender
Your mobile phone number is required for STATWISE™ text message symptom tracker.
Remove STATWISE™
Phone type

ENBREL Nurse Partners™ are ready to support you

ENBREL Nurse Partners™ will reach out to start your first one-on-one conversation.

When is your best time to be reached?

Amgen’s Privacy Pledge to Patients

  • Amgen respects patients and customers and takes the protection of their privacy very seriously. Amgen pledges the following:
  • Amgen does not and will not sell or rent your information to marketing companies or mailing list brokers.
  • Amgen is careful to only collect and/or use personal identifiable information for the purposes stated in this Authorization and as necessary to provide the services and/or programs the patient or customer chooses to enroll into.
  • Amgen practices are consistent with federal and state privacy laws, including HIPAA.
  • Amgen program enrollment is voluntary and always provides patients with an easy option to cancel participation.

Amgen’s Privacy Notice and Patient Authorization

Uses and Disclosure of Personal Information

I authorize Amgen and its contractors and business partners (“Amgen”) to use and/or disclose my personal information, including my personal health information, only for the following purposes:

  • To operate, administer, enroll me in, and/or continue my participation in Amgen’s ENBREL Support® program or any other Amgen-affiliated patient support services and activities related to my condition or treatment (for example, co-pay card programs, reimbursement assistance programs, drug coverage verification, nurse educator services, adherence program and disease management support);
  • To contact, with my permission, my doctor and the rest of my health care team and share with them my health information that may be useful for my care;
  • To provide me with informational and promotional materials relating to Amgen products and services, and/or my condition or treatment; and/or
  • To improve, develop, and evaluate products, services, materials and programs related to my condition or treatment.

In order for Amgen to provide me with the services and/or programs described above, Amgen needs to collect and use my personal information, including my personal health information. I understand that my personal health information may include any information, in electronic or physical form, in the possession of or derived from a health care provider, health care plan, pharmacy, pharmaceutical company, laboratory and/or their contractor (“Health Care Provider”). This may include select information from or about my medical history and general health, my health care plan benefits, payment limits or restrictions covered by my health care plan policy, and/or my adherence to my treatment.

By clicking the “I Accept” button, I am electronically indicating that I have read and understood Amgen’s Privacy Notice and Patient Authorization (above in its full text), that I am legally authorized to consent and that I am providing my consent as the patient or the patient’s legal representative for Amgen and its contractors and business partners to use and share the personal information I provide for the purposes described within the Privacy Notice and Authorization.

By clicking “I Decline” below, my activation and enrollment into ENBREL Support® will be discontinued.

Voicemail Consent

I give Amgen permission to leave a voice message that refers to the ENBREL Support® program by name and may include personal health information about my condition or treatment.

Amgen may contact me using the contact information provided in this form for participation in market research activities associated with Amgen’s products, services, and/or my condition or treatment. Please check one of the boxes below.

You must complete all required information above to proceed.

You're almost done!

Complete your Enbrel® Co-Pay Card enrollment by providing your prescription insurance information below.

prescription card

This is the card you will use to pay for your prescriptions. Please provide the information you need printed on your card.

*Required

You must complete all required information above to proceed.
prescription card

This is the card you will use to pay for your prescriptions. Please provide the information you need printed on your card.

Don’t have your prescription insurance information? No problem.

Simply call your prescription insurance provider for this information, then give the ENBREL Support® team a call at 1-888-4ENBREL (1-888-436-2735).

We will be unable to process your Enbrel® Co-Pay Card until we receive this information.

Click Finish, and we’ll save all the information you’ve provided. If you don’t have your Prescription Insurance Card information, simply select Skip This Step and contact ENBREL Support® to complete your enrollment.

Please try again, or contact the ENBREL Support® team at 1-888-4ENBREL.

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Enbrel® Co-Pay Card

Congratulations! Based on the information you provided, you are eligible for this card. You should receive your activated card in 2-3 business days. Please have this card ready when paying for your ENBREL medication.

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Thank you for your interest in the Enbrel® Co-Pay Card

It appears that we need to gather more information from you.

Please contact the ENBREL Support® team at 1-888-4ENBREL (1-888-436-2735) for further assistance. Our team is ready to help Monday-Sunday, 8 AM-11 PM ET.

Enbrel phone icon

Thank you for your interest in the Enbrel® Co-Pay Card

Based on the information you provided, we're unable to complete your enrollment online.

Please contact the ENBREL Support® team at 1-888-4ENBREL (1-888-436-2735) for further assistance. Our team is ready to help Monday-Sunday, 8 AM-11 PM ET.

Enbrel phone icon

You indicated you have government-provided insurance

Based on the information you provided, we’re unable to complete your enrollment online.

Our team of Medicare Solutions Specialists know about Medicare and can help you understand your Medicare coverage, including the donut hole and anticipating annual out-of-pocket costs for ENBREL. We can also help you find answers to other questions you may have about ENBREL and your Medicare Part D or Medicaid plan, and more.

Please contact the ENBREL Support® team at 1-888-4ENBREL (1-888-436-2735) for further assistance. Our team is ready to help Monday-Sunday, 8 AM-11 PM ET.

Enbrel question icon

You've indicated you don't currently have insurance

The Amgen Safety Net Foundation is an independent, nonprofit, patient assistance program that helps patients with financial need gain access to ENBREL at no cost.

Learn More
Enbrel question icon

You indicated you're not sure of your insurance coverage

Please contact the ENBREL Support® team at 1-888-4ENBREL (1-888-436-2735) for further assistance. Our team is ready to help Monday-Sunday, 8 AM-11 PM ET.

Following are the resources and services you have selected:

Establishing Your ENBREL Routine

Below are the resources you selected to help you get started with your ENBREL treatment routine. And remember, if you have any questions along the way, ENBREL Support® is just a call away at 1-888-4-ENBREL.

emwat emwat

Enbrel Mini® Cartridge with AutoTouch® Autoinjector

Watch this video to supplement the information you got from your doctor on how to use the Enbrel Mini® cartridge with AutoTouch® autoinjector. This video does not replace the Instructions for Use, which cover everything you need to know about how to use the Enbrel Mini® cartridge with AutoTouch® autoinjector.

Enbrel Mini® cartridge with AutoTouch® autoinjector Instructions for Use Medication Guide
autoinjector autoinjector

SureClick® Autoinjector Video

Watch the video below to see how the SureClick® Autoinjector works.

SureClick® Autoinjector Instructions for Use Medication Guide
pfs pfs

Prefilled Syringe

Watch this short video to see how the prefilled syringe works.

Prefilled syringe Instructions for Use Medication Guide
single dose vial single dose vial

Single-Dose Vial

A ready-to-use formulation. Review the instructions for Use, which cover everything you need to know about how to use the single-dose vial.

Single-dose vial Instructions for Use Medication Guide
emwat emwat

ENBREL supplement injection demo videos

Learn more about different injection options and watch demonstration videos to see how each device works.

Watch the videos
nurse partner

ENBREL Nurse Partners

ENBREL Nurse Partners™ provide one-on-one support to help establish your ENBREL treatment routine.

  • One-on-one supplemental injection training
  • Information about available ENBREL Support® services
  • Information about ENBREL and your condition

ENBREL Nurse Partners™ are nurses by training, but they are not part of your treatment team or an extension of your doctor’s office. ENBREL Nurse Partners™ do not inject patients with ENBREL. You will be referred to your doctor’s office for clinical advice.

One of our ENBREL Nurse Partners™ will be reaching out to you within 1-2 business days.

Enbrel guide

My ENBREL Guide

You will receive your copy of My ENBREL Guide via mail in 3-5 business days. In the meantime, you can download an electronic copy.

Download
Statwise

STATWISE™ Symptom Tracker

You will receive a welcome text message on your mobile phone and 4 additional text messages that will provide you with important program terms. After you have read those messages carefully, reply START to the last message to accept the terms and confirm your enrollment in the STATWISE™ program. You will receive a text message confirming your enrollment. Then you will start receiving the STATWISE™ program text messages the next day.

For detailed instructions, go to the Instructions & FAQs page.

Additional Resources

Condition management guide

ENBREL Condition Management Guide

In this guide, you’ll get information about what you might expect during your first 3 months of treatment with ENBREL. You’ll also find questions that can help you and your doctor identify treatment goals and ways to track your progress.

Download Download Download Download
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Important Safety Information

What is the most important information I should know about ENBREL?

ENBREL is a medicine that affects your immune

ENBREL is a medicine that affects your immune system. ENBREL can lower the ability of your immune system to fight infections. Serious infections
have happened in patients taking ENBREL. These infections include tuberculosis (TB) and infections caused by viruses, fungi, or bacteria that have

 
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Prescription Enbrel® (etanercept) is taken (given) by injection.

Important Safety Information

What is the most important information I should know about ENBREL?

ENBREL is a medicine that affects your immune system. ENBREL can lower the ability of your immune system to fight infections. Serious infections have happened in patients taking ENBREL. These infections include tuberculosis (TB) and infections caused by viruses, fungi, or bacteria that have spread throughout the body. Some patients have died from these infections. Your healthcare provider should test you for TB before you take ENBREL and monitor you closely for TB before, during, and after ENBREL treatment, even if you have tested negative for TB.

There have been some cases of unusual cancers, some resulting in death, reported in children and teenage patients who started using tumor necrosis factor (TNF) blockers before 18 years of age. Also, for children, teenagers, and adults taking TNF blockers, including ENBREL, the chances of getting lymphoma or other cancers may increase. Patients with RA may be more likely to get lymphoma.

Before starting ENBREL, tell your healthcare provider if you:

  • Have any existing medical conditions
  • Are taking any medicines, including herbals
  • Think you have, are being treated for, have signs of, or are prone to infection. You should not start taking ENBREL if you have any kind of infection, unless your healthcare provider says it is okay
  • Have any open cuts or sores
  • Have diabetes, HIV, or a weak immune system
  • Have TB or have been in close contact with someone who has had TB
  • Were born in, lived in, or traveled to countries where there is more risk for getting TB. Ask your healthcare provider if you are not sure
  • Live, have lived in, or traveled to certain parts of the country (such as, the Ohio and Mississippi River valleys, or the Southwest) where there is a greater risk for certain kinds of fungal infections, such as histoplasmosis. These infections may develop or become more severe if you take ENBREL. If you don’t know if these infections are common in the areas you’ve been to, ask your healthcare provider
  • Have or have had hepatitis B
  • Have or have had heart failure
  • Develop symptoms such as persistent fever, bruising, bleeding, or paleness while taking ENBREL
  • Use the medicine Kineret (anakinra), Orencia (abatacept), or Cytoxan (cyclophosphamide)
  • Are taking anti-diabetic medicines
  • Have, have had, or develop a serious nervous disorder, seizures, any numbness or tingling, or a disease that affects your nervous system such as multiple sclerosis or Guillain-Barré syndrome
  • Are scheduled to have surgery
  • Have recently received or are scheduled for any vaccines. All vaccines should be brought up-to-date before starting ENBREL. Patients taking ENBREL should not receive live vaccines.
  • Are allergic to rubber or latex
  • Are pregnant, planning to become pregnant, or breastfeeding
  • Have been around someone with chicken pox

What are the possible side effects of ENBREL?

ENBREL can cause serious side effects including: New infections or worsening of infections you already have; hepatitis B can become active if you already have had it; nervous system problems, such as multiple sclerosis, seizures, or inflammation of the nerves of the eyes; blood problems (some fatal); new or worsening heart failure; new or worsening psoriasis; allergic reactions; autoimmune reactions, including a lupus-like syndrome and autoimmune hepatitis.

Common side effects include: Injection site reactions and upper respiratory infections (sinus infections).

In general, side effects in children were similar in frequency and type as those seen in adult patients. The types of infections reported were generally mild and similar to those usually seen in children.

These are not all the side effects with ENBREL. Tell your healthcare provider about any side effect that bothers you or does not go away.

If you have any questions about this information, be sure to discuss them with your healthcare provider. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Please see Prescribing Information and Medication Guide.

Indications

Moderate to Severe Rheumatoid Arthritis (RA)

ENBREL is indicated for reducing signs and symptoms, keeping joint damage from getting worse, and improving physical function in patients with moderately to severely active rheumatoid arthritis. ENBREL can be taken with methotrexate or used alone.

Psoriatic Arthritis

ENBREL is indicated for reducing signs and symptoms, keeping joint damage from getting worse, and improving physical function in patients with psoriatic arthritis. ENBREL can be used with or without methotrexate.

Moderate to Severe Plaque Psoriasis

ENBREL is indicated for chronic moderate to severe plaque psoriasis (PsO) in children 4 years and older and adults who may benefit from taking injections or pills (systemic therapy) or phototherapy (ultraviolet light).

Ankylosing Spondylitis (AS)

ENBREL is indicated for reducing signs and symptoms in patients with active ankylosing spondylitis.

Moderately to Severely Active Polyarticular Juvenile Idiopathic Arthritis (JIA)

ENBREL is indicated for reducing signs and symptoms of moderately to severely active polyarticular juvenile idiopathic arthritis (JIA) in children ages 2 years and older.

References: 1. Parsabiv® (etelcalcetide) prescribing information, Amgen. 2. Data on file, Amgen; [Summary of Clinical Efficacy; 2015]. 3. Alexander ST, et al. Mol Pharmacol. 2015;88:853-865. 4. Data on file, Amgen; [Report R20130052, 2014]. 5. Chen P, et al. CPT Pharmacometrics Syst Pharmacol. 2016;5:484-494. 6. Sensipar® (cinacalcet) prescribing information, Amgen. 7. Ma JN, et al. J Pharmacol Exp Ther. 2011;337:275-284.
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