Indications

ENBREL is indicated for reducing signs and symptoms, keeping joint damage from getting worse, and improving physical function in patients with moderately to severely active rheumatoid arthritis. ENBREL can be taken with methotrexate or used alone. Read more

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ON ENBREL?

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things to keep in mind.

  • Co-pay re-enrollment

    ENBREL CO-PAY CARD RE-ENROLLMENT

    In order to continue in the ENBREL Co-Pay Program, patients must continue to meet all of the program's eligibility requirements and re-enroll at regular intervals. Re-enroll in a few steps—start by filling out the form below.

    Verification Step

    First, we’ll make sure that your current ENBREL Co-Pay Card information matches what’s in our system. All information is required unless otherwise noted.

    Amgen® SupportPlus for ENBREL®

    Patients or caregivers must be 18 years of age or older to enroll online. Please Confirm your age below.

    Date of birth is required
    Please enter a valid date
    We're sorry—you must be 18 years or older to enroll.

    Choose Your Insurance

    Great! Don't forget to fill out your insurance information on the next tab so that we can help finalize your enrollement.

    Are you eligible for Medicare but receive prescription drug coverage from a former employer, union, or welfare plan?

    By checking this box, I agree that I read, understand, and accept the Terms and Conditions of the Enbrel Co-Pay Program

    Great! You’ll have access to all our helpful patient support resources, like injecting assistance and tracking tools. Amgen SupportPlus representative can help you understand your current Medicare insurance plan and anticipated out-of-pocket costs for Enbrel. If you want to switch Medicare plans, we can help identify other local options. We may also be able to refer you, if eligible, for Medicare Extra Help (Low Income Subsidy) or put you in touch with independent nonprofit foundations.*

    *Eligibility for resources provided by independent nonprofit patient assistance programs is based on the nonprofit’s criteria. Amgen has no control over these programs and provides information as a courtesy only.

    If you are uninsured or underinsured, Amgen® Safety Net Foundation is a nonprofit patient assistance program sponsored by Amgen® that helps qualifying patients access Amgen medicines at no cost. Click here to learn more.

    *Eligibility for resources provided by independent nonprofit patient assistance programs is based on the nonprofit’s criteria. Amgen has no control over these programs and provides information as a courtesy only.

    Patient Information

    Has any of your personal information (including contact information and/or insurance information) changed since you last enrolled in the ENBREL Co-Pay program?

    State is required
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    Entered Address:
    Suggested Address:

    Amgen Patient Authorization

    Uses and Disclosure of Personal Information

    I authorize Amgen and its contractors and business partners (“Amgen”) to use and/or disclose my personal information, including my personal health information, only for the following purposes:

    • To operate, administer, enroll me in, and/or continue my participation in Amgen® SupportPlus program or any other Amgen-affiliated patient support services and activities related to my condition or treatment (for example, co-pay programs, reimbursement assistance programs, drug coverage verification, nurse educator services, adherence program and disease management support);
    • To contact, with my permission, my doctor and the rest of my health care team and share with them my health information that may be useful for my care;
    • To provide me with informational and promotional materials relating to Amgen products and services, and/or my condition or treatment; and/or
    • To improve, develop, and evaluate products, services, materials and programs related to my condition or treatment.

    In order for Amgen to provide me with the services and/or programs described above, Amgen needs to collect and use my personal information, including my personal health information. I understand that my personal health information may include any information, in electronic or physical form, in the possession of or derived from a health care provider, health care plan, pharmacy, pharmaceutical company, laboratory and/or their contractor (“Health Care Provider”). This may include select information from or about my medical history and general health, my health care plan benefits, payment limits or restrictions covered by my health care plan policy, and/or my adherence to my treatment. I authorize my Health Care Providers to disclose my personal health information to Amgen, and between themselves, as necessary, but only for the purposes stated above in this Authorization. I understand that certain of my Health Care Providers (such as pharmacies and specialty pharmacies) may receive remuneration from Amgen in exchange for disclosing my personal health information and/or for using my information to contact me with communications about Amgen products which have been prescribed to me (for example medication reminder programs) and other patient support services.

    Expiration, Right to Obtain a Copy and Right to Cancel

    I understand that by signing this form, I authorize my Health Care Providers or others who might hold my health information to only release it to Amgen employees, as well as to its contractors and business partners, who are performing the services set forth in this Authorization. I also understand I am authorizing my personal information, including my personal health information, to be used for the purposes described above. I understand and agree that by signing below, I am authorizing those who rely on this Authorization to release my personal health information for the earlier of five (5) years or until my participation in the program ends through my cancellation, unless a shorter time period is required by state law.

    I understand that I can obtain a copy of this Authorization or cancel this Authorization at any time by calling Amgen SupportPlus at 1-833-44AMGEN (1-833-442-6436) or by writing to PO BOX 2135, Morristown, NJ 07962-9927. If I cancel my consent, I will no longer qualify for the services described. I also understand that if a Health Care Provider is disclosing my personal health information to Amgen on an authorized on-going basis, my cancellation with Amgen will be effective with respect to any such Health Care Providers as soon as they receive notice of my cancellation.

    No Effect on Treatment

    I understand I do not have to sign this Authorization and that my enrollment in any of the services and/or programs described above is entirely voluntary. I understand that Amgen, as well as Health Care Providers, cannot require me, as a condition of having access to medications, prescription drugs, treatment or other care, to sign this Authorization. Federal Law (including HIPAA) requires a signed authorization in order for Amgen to collect this information from my Health Care Providers. I understand I cannot participate in the listed services and/or programs without signing this Authorization or an equivalent authorization with my Health Care Providers.

    Information Received from Health Care Providers

    I understand that once my personal health information has been disclosed to Amgen, federal privacy laws may no longer apply and protect it from further disclosure. Amgen agrees, however, to protect my personal health information by only using and disclosing it as stated in the Authorization or as otherwise allowed or required by law.

    Authorization to Contact

    I understand and consent to Amgen contacting me using the contact information provided in this form to enroll me in, operate, and administer Amgen patient support services and/or programs as described above other than promotional communications by telephone or SMS/text (which I can separately opt-in below). I understand that the operation and administration of certain of these services and/or programs may require that Amgen contact me by telephone or SMS/text.

    By clicking the "I agree" button, I am electronically indicating that I have read and understood Amgen's Patient Authorization (above in its full text), that I am legally authorized to consent and that I am providing my consent as the patient or the patient's legal representative for Amgen and its contractors and business partners to use and share the personal information I provide for the purposes described within the Patient Authorization. By clicking the "I disagree" button, my activation and enrollment into Amgen SupportPlus will be discontinued.

    Applicable if healthcare provider is assisting. By clicking the "I agree" button, I represent and am electronically indicating that the patient read and understood Amgen's Patient Authorization (above in its full text) and that I am acknowledging the patient's consent on their behalf. I further represent that I received consent from the patient to disclose their personal health information to Amgen and its contractors and business partners for them to use and share the personal information the patient provided for the purposes described within the Patient Authorization. A copy of the Patient Authorization will be provided to the patient via email. By clicking the “I disagree” button below, the patient’s activation and enrollment into Amgen SupportPlus will be discontinued.

    Commercial Insurance? Let Us Do the Talking

    If you have commercial insurance, you can enter in your insurance information below now—and save time later. Providing this info will allow us to reach out to your insurance company on your behalf if any coverage-related questions come up in the future.

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    Congratulations!

    Your Co-Pay card has been renewed!

    Amgen® SupportPlus for ENBREL® Co-Pray Program

    RxBIN: XXXXXX

    PCN: XX

    Group: XXXXXXXXXX

    Member ID: XXXXXXXXXXX

    Check your email for your ENBREL Co-Pay Card information.

    Questions about your insurance or want to make changes?

    Our Amgen® SupportPlus Representatives are happy to help. Call us at 1-888-4ENBREL (1-888-436-2735), 8 AM–8 PM ET.

    Thank you for your interest in ENBREL Co-Pay RE-ENROLLMENT.

    Based on the information you provided, we’re unable to re-enroll in your ENBREL Co-Pay Card online.

    Please contact the Amgen® SupportPlus team at 1-888-4ENBREL (1-888-436-2735) so we can further assist you in the re-enrollment process. Our team is ready to help Monday–Friday from 8 AM to 8 PM (ET).

  • Amgen® Nurse Partner

    Support from an Amgen® Nurse PARTNER*

    For patients looking for one-on-one support, Amgen Nurse Partners are here to help. Amgen Nurse Partners can provide supplemental support at no cost to you as an ENBREL patient:

    • One-on-one support to help you get more comfortable injecting on your own,* available virtually
    • General information about your condition, how ENBREL works, and the Important Safety Information
    • Answers to frequently asked questions on topics such as traveling with ENBREL, storage, and establishing your treatment routine
    • Guidance on resources that may help lower out-of-pocket medication costs

    Amgen Nurse Partners are available to patients who have enrolled in support from ENBREL. Not enrolled yet? Get started here.

    *Amgen Nurse Partners are only available to patients that are prescribed certain Amgen products. They are not part of your treatment team and do not provide medical advice, nursing, or case management services. Amgen Nurse Partners will not inject patients with Amgen medications. Patients should always consult their healthcare provider regarding medical decisions or treatment concerns

    Amgen Nurse Partners are available to patients who have enrolled in support from ENBREL. Not enrolled yet? Get started here.

    *Amgen Nurse Partners are only available to patients that are prescribed certain Amgen products. They are not part of your treatment team and do not provide medical advice, nursing, or case management services. Amgen Nurse Partners will not inject patients with Amgen medications. Patients should always consult their healthcare provider regarding medical decisions or treatment concerns

    • Indication

      ENBREL® (etanercept) is indicated for the treatment for patients with moderately to severely active rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, moderate to severe plaque psoriasis in adults and children

      4 years and older, and moderately to severely active polyarticular juvenile idiopathic arthritis.

      VO:

      NURSE: Hello?

      GRACE: My name is Grace and I’m a new patient starting on ENBREL. I recently enrolled in the ENBREL Nurse Partner™ program through ENBREL® Support. Thank you for taking the time to talk to me. I received injection training from my doctor’s office, but I’m a little nervous about administering ENBREL all by myself.

      NURSE: I completely understand. It’s okay to feel a little nervous about injecting ENBREL. I understand you may still be nervous about injecting after you received injection training in your doctor’s office. I can help you with that. Our team of experienced ENBREL Nurse Partners™ are more than happy to provide supplemental injection support. They can talk you through the process over the phone or, depending where you live, an ENBREL Nurse Partner™ can also come to your home for one-on-one support in person. They can also help you establish a routine for your injection. It is important to think of a good time and day of the week that allows you to take ENBREL without interruptions. So just when you’re watching your favorite weekly TV show, you can also set a weekly alarm for that time. Remember, you need to take ENBREL out of the refrigerator. ENBREL Nurse Partners™ can provide information about ENBREL as well as answer questions related to travel and storage and connect you to other useful ENBREL resources. If you like, you can also review the Instructions for Use or watch the injection demonstration videos at injectingenbrel.com. You can also download the Embark® App to quickly access ENBREL® Support services and set refill and appointment reminders. Remember, if you have medical questions about your symptoms, conditions, or how you’re feeling, contact your doctor’s office. Remember, ENBREL Nurse Partners™ are here to answer your questions about ENBREL and provide supplemental injection support. Contact ENBREL® Support to enroll today.

  • Embark® App

    Download the Embark App

    Put medication reminders, injection site tracking, and more—all in the palm of your hand.

    Download the free Embark App to help you create and maintain your injection routine, and get access to ENBREL patient support and resources all in one place. Key features of the app include:

    Support from ENBREL

    • Eligible commercially insured patients can enroll in the Co-Pay Card program and view their remaining benefit and transaction history*
    • Review ENBREL medication and safety information
    • Watch injection demonstration videos to see how ENBREL works

    *might not reflect recent or pending transactions

    Medication reminders

    • Create a treatment calendar to schedule reminders for ENBREL and any other medications you may be taking
    • Schedule notifications for doctor visits, refills, and more

    ENBREL injection tracking

    • Track injection sites on your body to help you stay on top of your routine and to easily share that information with your healthcare team
    • Patients with rheumatoid arthritis or psoriatic arthritis can track their symptoms with STATWISE™

    MEET THE EMBARK APP

    Watch this short video for an overview of the Embark App's many helpful features

    • read video transcript

      Indication

      ENBREL® (etanercept) is indicated for the treatment for patients with moderately to severely active rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, moderate to severe plaque psoriasis in adults and children 4 years and older, and moderately to severely active polyarticular juvenile idiopathic arthritis.

      VO:

      Welcome to ENBREL® (etanercept). Beginning a new treatment comes with a lot of questions. We get it. That’s why we created the Embark® App. To make it easier to get started. And support you along the way. Access Financial Support Information. Access Medication Reminders. Access Injection Site Tracking. And much more. All in the palm of your hand. Looking for financial support? Eligible commercially insured patients can sign up for the ENBREL Co-Pay Card.* Eligibility criteria and program limits apply. Eligible commercially insured patients may pay as little as $5 per month. Preparing for your injection? The Embark® App can help with that. Watch demo videos on the different ways to inject ENBREL. Demonstration videos are played from Enbrel.com. Prefer a personal touch? Enroll in the ENBREL Nurse Partner™ program. ENBREL Nurse Partners™ do not inject patients with ENBREL. Patients will be referred to their doctor’s office for clinical advice. An ENBREL Nurse Partner™ can provide support over the phone. Or come to your home to provide support in person. Need help staying organized when life gets busy? Let the Embark® App give you a hand. It can remind you to take your ENBREL. It can remind you to take your other medications, too. It can remind you to refill your ENBREL. It’s important to alternate injection sites on your body each time. But do you remember where you injected last week? The Embark® App does. It remembers so you don’t have to. It can be easy to overlook changes in your key symptoms. STATWISE™ helps you keep track of your key symptoms if you have moderate to severe rheumatoid arthritis or psoriatic arthritis. You can sign up for STATWISE™ through the Embark® App. Embark® from ENBREL® (etanercept) Support to help, whenever, wherever you need it. Download for free today.

      *Please see enbrelsupport.com for full terms and conditions.

      ENBREL Nurse Partners™ are nurses by training, but they are not part of a patient's treatment team or an extension of their doctor’s office.

      When you record that information in the app.

    QR Code

    Download the Embark App for free:

    Simply scan this QR code.

    You can also download the Embark App here:

  • Travel and storage

    Tips for traveling with your ENBREL medication

    When traveling with your ENBREL, it’s important not to miss your injections, so please keep the following in mind:

    ENBREL can be kept at room temperature (between 68°F to 77°F) for up for 30 days. It cannot be put back in the fridge once it reaches room temperature, so keep this in mind when making travel plans.

    If you’ve not received a travel kit already, you can request one by calling us at 1-888-4-ENBREL
    (1-888-436-2735)

    • What to bring in a travel bag

      • Your ENBREL medication
      • ENBREL syringes or injectors in their original containers
      • A sharps container for easy needle disposal
      • ENBREL Travel Kit
      • A copy of your prescription
    • How to store ENBREL on a trip

      • ENBREL can be stored at room temperature (between 68°F to 77°F) for up to 30 days
        • If you’re traveling somewhere with extreme heat or cold, or if you will be traveling for more than 30 days, please contact us or your specialty pharmacy before your trip for guidance on refrigeration while traveling
      • Pack ENBREL in carry-on baggage in a zip-top bag
      • Refrain from shaking your ENBREL
      • Always keep your ENBREL and other medicines out of the reach of children
      • You can request an ENBREL Travel Kit to help you
    • How to navigate security
      checkpoints

      • At the start of the screening process, tell the TSA officer that you have medically required liquids in a zip-top bag
      • Your ENBREL medication may be subject to additional screening, which may include opening the medication container
      • Medications in liquid form in excess of 3.4 ounces are allowed in carry-on baggage at reasonable quantities
      • Medication is usually screened by X-ray. X-ray screeners at TSA checkpoints should not affect your ENBREL. However, you may ask beforehand for a hand inspection
      • Be sure to review the TSA Travel Guidelines for the most current regulations
  • Caring for yourself

    Caring for Yourself

    In addition to following your doctor’s treatment plan, make sure you are taking care of YOU. That can include taking the time to make positive and healthy lifestyle choices and thinking about ways you can help to self-manage your condition, both physically and emotionally.

    While these choices won’t necessarily impact how ENBREL works for you, they may make a difference in how your condition impacts your day-to-day activities and your outlook.

    Having things like the right fitness plan and/or diet and a positive attitude can go a long way towards helping manage your condition.

    Here are some tips that may help you:

    Staying active

    Exercising may be the last thing on your mind, especially if you are experiencing severe symptoms. But with symptom relief, you may be thinking how you can return to activities that are important to you, including exercise.

    Make sure you talk with your doctor to come up with a plan to increase your physical activity together. Be sure to keep communicating with your doctor about how it’s going and what changes you can make over time.

    Healthy diet

    A healthy diet can go a long way. Try introducing a diet that’s low in processed foods and saturated fats and replacing them with anti-inflammatory foods like berries, cherries, and leafy greens. Remember to talk to your doctor about making any changes to your diet.

    Keeping positive

    Savor the little things! Celebrate the little things, from opening a jar to spending an afternoon with loved ones.

    • Don’t sweat the small stuff:
      • When symptoms are flaring or you’re not feeling well, give yourself permission to take care of yourself
    • Keep things in perspective:
      • Some days, you may get angry because things take longer to do, or you just can’t do them all together, and that’s okay. The chronic nature of your condition means there will be tough days, but take things at your own pace and don’t feel bad about it
    • Planning ahead:
      • Planning things out ahead of time can be very important when managing your condition. On your good days, take time to prepare for any bad days ahead, such as preparing future meals or working on activities that may be harder to do on your bad days

Prescription Enbrel® (etanercept) is taken (given) by injection.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about ENBREL?

ENBREL is a medicine that affects your immune system. ENBREL can lower the ability of your immune system to fight infections. Serious infections have happened in patients taking ENBREL. These infections include tuberculosis (TB) and infections caused by viruses, fungi, or bacteria that have spread throughout the body. Some patients have died from these infections. Your healthcare provider should test you for TB before you take ENBREL and monitor you closely for TB before, during, and after ENBREL treatment, even if you have tested negative for TB.

There have been some cases of unusual cancers, some resulting in death, reported in children and teenage patients who started using tumor necrosis factor (TNF) blockers before 18 years of age. Also, for children, teenagers, and adults taking TNF blockers, including ENBREL, the chances of getting lymphoma or other cancers may increase. Patients with RA may be more likely to get lymphoma.

Before starting ENBREL, tell your healthcare provider if you:

  • Have any existing medical conditions
  • Are taking any medicines, including herbals
  • Think you have, are being treated for, have signs of, or are prone to infection. You should not start taking ENBREL if you have any kind of infection, unless your healthcare provider says it is okay
  • Have any open cuts or sores
  • Have diabetes, HIV, or a weak immune system
  • Have TB or have been in close contact with someone who has had TB
  • Were born in, lived in, or traveled to countries where there is more risk for getting TB. Ask your healthcare provider if you are not sure
  • Live, have lived in, or traveled to certain parts of the country (such as, the Ohio and Mississippi River valleys, or the Southwest) where there is a greater risk for certain kinds of fungal infections, such as histoplasmosis. These infections may develop or become more severe if you take ENBREL. If you don’t know if these infections are common in the areas you’ve been to, ask your healthcare provider
  • Have or have had hepatitis B
  • Have or have had heart failure
  • Develop symptoms such as persistent fever, bruising, bleeding, or paleness while taking ENBREL
  • Use the medicine Kineret (anakinra), Orencia (abatacept), or Cytoxan (cyclophosphamide)
  • Are taking anti-diabetic medicines
  • Have, have had, or develop a serious nervous disorder, seizures, any numbness or tingling, or a disease that affects your nervous system such as multiple sclerosis or Guillain-Barré syndrome
  • Are scheduled to have surgery
  • Have recently received or are scheduled for any vaccines. All vaccines should be brought up-to-date before starting ENBREL. Patients taking ENBREL should not receive live vaccines
  • Are allergic to rubber or latex
  • Are pregnant, planning to become pregnant, or breastfeeding
  • Have been around someone with chicken pox

What are the possible side effects of ENBREL?

ENBREL can cause serious side effects including: New infections or worsening of infections you already have; hepatitis B can become active if you already have had it; nervous system problems, such as multiple sclerosis, seizures, or inflammation of the nerves of the eyes; blood problems (some fatal); new or worsening heart failure; new or worsening psoriasis; allergic reactions; autoimmune reactions, including a lupus-like syndrome and autoimmune hepatitis.

Common side effects include: Injection site reactions and upper respiratory infections (sinus infections).

In general, side effects in children were similar in frequency and type as those seen in adult patients. The types of infections reported were generally mild and similar to those usually seen in children.

These are not all the side effects with ENBREL. Tell your healthcare provider about any side effect that bothers you or does not go away.

If you have any questions about this information, be sure to discuss them with your healthcare provider. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Please see Prescribing Information and Medication Guide.

INDICATIONS

Moderate to Severe Rheumatoid Arthritis (RA)

ENBREL is indicated for reducing signs and symptoms, keeping joint damage from getting worse, and improving physical function in patients with moderately to severely active rheumatoid arthritis. ENBREL can be taken with methotrexate or used alone.

Psoriatic Arthritis

ENBREL is indicated for reducing signs and symptoms, keeping joint damage from getting worse, and improving physical function in patients with psoriatic arthritis. ENBREL can be used with or without methotrexate.

Moderate to Severe Plaque Psoriasis

ENBREL is indicated for chronic moderate to severe plaque psoriasis (PsO) in children 4 years and older and adults who may benefit from taking injections or pills (systemic therapy) or phototherapy (ultraviolet light).

Ankylosing Spondylitis (AS)

ENBREL is indicated for reducing signs and symptoms in patients with active ankylosing spondylitis.

Moderately to Severely Active Polyarticular Juvenile Idiopathic Arthritis (JIA)

ENBREL is indicated for reducing signs and symptoms of moderately to severely active polyarticular juvenile idiopathic arthritis (JIA) in children ages 2 years and older.

Prescription Enbrel® (etanercept) is taken (given) by injection.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about ENBREL?

ENBREL is a medicine that affects your immune system. ENBREL can lower the ability of your immune system to fight infections.