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Indications

ENBREL is indicated for reducing signs and symptoms, keeping joint damage from getting worse, and improving physical function in patients with moderately to severely active rheumatoid arthritis. ENBREL can be taken with methotrexate or used alone. Read More

ENBREL is indicated for chronic moderate to severe plaque psoriasis (PsO) in children 4 years and older and adults who may benefit from taking injections or pills (systemic therapy) or phototherapy (ultraviolet light). 
ENBREL is indicated for reducing signs and symptoms, keeping joint damage from getting worse, and improving physical function in patients with psoriatic arthritis. ENBREL can be used with or without methotrexate.
ENBREL is indicated for reducing signs and symptoms in patients with active ankylosing spondylitis. 
ENBREL is indicated for reducing signs and symptoms of moderately to severely active polyarticular juvenile idiopathic arthritis (JIA) in children ages 2 years and older. Close

ENBREL® SupportPlus Enrollment

Congrats! You're now enrolled in ENBREL®SupportPlus.

We're sorry, but an error has occurred.

Now that you have been prescribed ENBREL, your next step is to enroll in ENBREL® SupportPlus. All of the services and resources available to you through ENBREL® SupportPlus are designed to help patients like you start and stay on your new ENBREL treatment as prescribed.

ENBREL® SupportPlus enrollment is an easy way to sign up for resources that can help you establish and maintain your ENBREL treatment routine.

Ready to get started?

For which condition did your doctor prescribe ENBREL?

Sorry, you must have an ENBREL prescription to enroll. Talk to your doctor to see if ENBREL is right for you.

There are just 3 easy steps to select the resources and services that are best for you.

Let’s start by looking at resources to help pay for ENBREL

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Options for Paying for ENBREL

One of the first questions people ask is, “How much does ENBREL cost?” That’s why our financial resource specialists are there to make sure you’ve got the right information and the right kind of support based on your insurance status. Start by answering the following questions.

What best describes the type of prescription insurance you have?

The Enbrel® Co-Pay Card can help reduce out-of-pocket costs for eligible commercially insured patients.

Are you eligible for Medicare but receive prescription drug coverage from a former employer, union, or welfare plan?

By checking this box, I agree that I read, understand, and accept the Terms and Conditions of the Enbrel® Co-Pay Card.

Our team of Medicare Solutions Specialists know about Medicare and can help you understand your Medicare coverage, including the donut hole and anticipating annual out-of-pocket costs for ENBREL. We can also help you find answers to other questions you may have about ENBREL and your Medicare Part D or Medicaid plan, and more.

Their contact information will be provided after your enrollment is complete.

The Amgen Safety Net Foundation is a nonprofit patient assistance program sponsored by Amgen that helps qualifying patients access Amgen medicines at no cost.

Their contact information will be provided after your enrollment is complete.

Our team of Financial Resource Specialists may be able to help you figure out how to lower your out-of-pocket costs for ENBREL.

Their contact information will be provided after your enrollment is complete.

I’m not interested in financial options.

The next step is selecting your injection device and starting a treatment routine.

You must complete all required information above to proceed.
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Establishing Your Treatment Routine

Once you start treatment after your healthcare provider has trained you on how to inject and reviewed the Instructions for Use, it’s important to get into a consistent routine for administering your ENBREL medication. ENBREL has a number of resources to help you establish a good routine, including supplemental injection demo videos and one-on-one assistance from ENBREL Nurse Partners™.

To get started, please select which device you’ll use to inject your ENBREL medication.

ENBREL Nurse Partners

For additional assistance with establishing your ENBREL treatment routine, turn to one of our ENBREL Nurse Partners™, who can provide one-on-one support to help. ENBREL Nurse Partners™ can provide you help at home, by phone, email, or video chat. ENBREL Nurse Partners™ are nurses by training, but they are not part of your treatment team or an extension of your doctor’s office. ENBREL Nurse Partners™ do not inject patients with ENBREL. You will be referred to your doctor’s office for clinical advice.

Would you like to register for the ENBREL Nurse Partners™ program?

You’re just about done! There are a few more resources for your consideration that may also be helpful.

You must complete all required information above to proceed.

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Additional Resources

Whether you’re a new or experienced ENBREL patient or caregiver, we have an array of resources that can help you throughout your journey.


My Enbrel Guide

My ENBREL Guide

With the help of patients just like you, ENBREL® SupportPlus has created this clear, step-by-step guide to help you successfully get started on ENBREL.

You will receive a copy of My ENBREL Guide by mail within 3-5 business days. You will also receive a link to download when you complete your ENBREL® SupportPlus enrollment.

My ENBREL Guide has been added to your resources.


Embark App

Meet the Embark® App

The Embark App has been designed to support your ENBREL experience, offering financial support information, medication reminders, injection site tracking and more—all in the palm of your hand.

Download the app for free here:

Download the app for free by scanning this code with your camera.

QR code Google Play Apple App Store Google Play Apple App Store

Statwise Symptom Tracker

STATWISE™ Symptom Tracker

To help answer the question, "Is ENBREL working for me?" we've developed STATWISE™-a simple-to-use text message program that may help you to see signs you might be missing.

Take a few moments to respond to 3 text messages every day and rate your symptons. A STATWISE™ symptom report capturing your personal experience will be generated automatically every 2 weeks that may help you understand your progress with ENBREL and share your results with your doctor or loved ones.

Is your mobile phone a smartphone? (eg, iPhone or Android phone)

Please make a selection

Day of the week you will take your prescribed ENBREL injection

Day of the week is required

You’re almost done. The last step is to provide your personal information and complete your ENBREL Support ® Enrollment.

You must complete all required information above to proceed.

ENBREL® SupportPlus Enrollment

ENBREL® SupportPlus is ready to get you started with—and help you stay on—the treatment plan you’ve made with your doctor.

Following are the resources and services you have selected:

  • My ENBREL Guide
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    Add Back
  • STATWISE™ Symptom Tracker
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    Add Back

Patient Information

All information is required unless otherwise noted.

State is required
Date of birth is required
We're sorry—you must be 18 years or older to enroll. Please call ENBREL® SupportPlus to complete enrollment.

If you or your loved one is under 18 years of age, please call ENBREL® SupportPlus to complete enrollment.

Gender
Your mobile phone number is required for STATWISE™ text message symptom tracker.
Remove STATWISE™
Phone type

ENBREL Nurse Partners™ are ready to support you

ENBREL Nurse Partners™ will reach out to start your first one-on-one conversation.

When is your best time to be reached?

Amgen’s Patient Authorization

Uses and Disclosure of Personal Information

I authorize Amgen and its contractors and business partners (“Amgen”) to use and/or disclose my personal information, including my personal health information, only for the following purposes:

  • To operate, administer, enroll me in, and/or continue my participation in Amgen’s ENBREL® SupportPlus program or any other Amgen-affiliated patient support services and activities related to my condition or treatment (for example, co-pay card programs, reimbursement assistance programs, drug coverage verification, nurse educator services, adherence program and disease management support);
  • To contact, with my permission, my doctor and the rest of my health care team and share with them my health information that may be useful for my care;
  • To provide me with informational and promotional materials relating to Amgen products and services, and/or my condition or treatment; and/or
  • To improve, develop, and evaluate products, services, materials and programs related to my condition or treatment.

In order for Amgen to provide me with the services and/or programs described above, Amgen needs to collect and use my personal information, including my personal health information. I understand that my personal health information may include any information, in electronic or physical form, in the possession of or derived from a health care provider, health care plan, pharmacy, pharmaceutical company, laboratory and/or their contractor (“Health Care Provider”). This may include select information from or about my medical history and general health, my health care plan benefits, payment limits or restrictions covered by my health care plan policy, and/or my adherence to my treatment.

I authorize my Health Care Providers to disclose my personal health information to Amgen, and between themselves, as necessary, but only for the purposes stated above in this Authorization. I understand that certain of my Health Care Providers (such as pharmacies and specialty pharmacies) may receive remuneration from Amgen in exchange for disclosing my personal health information and/or for using my information to contact me with communications about Amgen products which have been prescribed to me (for example medication reminder programs) and other patient support services.

Expiration, Right to Obtain a Copy and Right to Cancel

I understand that by signing this form, I authorize my Health Care Providers or others who might hold my health information to only release it to Amgen employees, as well as to its contractors and business partners, who are performing the services set forth in this Authorization. I also understand I am authorizing my personal information, including my personal health information, to be used for the purposes described above. I understand and agree that by signing below, I am authorizing those who rely on this Authorization to release my personal health information for the earlier of five (5) years or until my participation in the program ends through my cancellation, unless a shorter time period is required by state law.

I understand that I can obtain a copy of this Authorization or cancel this Authorization at any time by calling Amgen at 888-436-2735 or by writing to PO Box 7249, Bedminster, NJ 07921. If I cancel my consent, I will no longer qualify for the services described. I also understand that if a Health Care Provider is disclosing my personal health information to Amgen on an authorized on-going basis, my cancellation with Amgen will be effective with respect to any such Health Care Providers as soon as they receive notice of my cancellation.

No Effect on Treatment

I understand I do not have to sign this Authorization and that my enrollment in any of the services and/or programs described above is entirely voluntary. I understand that Amgen, as well as Health Care Providers, cannot require me, as a condition of having access to medications, prescription drugs, treatment or other care, to sign this Authorization. Federal Law (including HIPAA) requires a signed authorization in order for Amgen to collect this information from my Health Care Providers. I understand I cannot participate in the listed services and/or programs without signing this Authorization or an equivalent authorization with my Health Care Providers.

Information Received from Health Care Providers

I understand that once my personal health information has been disclosed to Amgen, federal privacy laws may no longer apply and protect it from further disclosure. Amgen agrees, however, to protect my personal health information by only using and disclosing it as stated in the Authorization or as otherwise allowed or required by law.

Authorization to Contact

I understand and consent to Amgen contacting me using the contact information provided in this form to enroll me in, operate, and administer Amgen patient support services and/or programs as described above other than promotional communications by telephone or SMS/text (which I can separately opt-in below). I understand that the operation and administration of certain of these services and/or programs may require that Amgen contact me by telephone or SMS/text.

By clicking the “I Accept” button, I am electronically indicating that I have read and understood the Patient Authorization (above in its full text), that I am legally authorized to consent and that I am providing my consent as the patient or the patient’s legal representative for Amgen and its contractors and business partners to use and share the personal information I provide for the purposes described within the Privacy Notice and Authorization.

By clicking “I Decline” below, my activation and enrollment into ENBREL® SupportPlus will be discontinued.

Voicemail Consent

I give Amgen permission to leave a voice message that refers to the ENBREL® SupportPlus program by name and may include personal health information about my condition or treatment.

Amgen may contact me using the contact information provided in this form for participation in market research activities associated with Amgen’s products, services, and/or my condition or treatment. Please check one of the boxes below.

You must complete all required information above to proceed.

You're almost done!

Complete your Enbrel® Co-Pay Card enrollment by providing your prescription insurance information below.

prescription card

This is the card you will use to pay for your prescriptions. Please provide the information you need printed on your card.

*Required

You must complete all required information above to proceed.
prescription card

This is the card you will use to pay for your prescriptions. Please provide the information you need printed on your card.

Don’t have your prescription insurance information? No problem.

Simply call your prescription insurance provider for this information, then give the ENBREL Support ® team a call at 1-888-4ENBREL (1-888-436-2735).

We will be unable to process your Enbrel® Co-Pay Card until we receive this information.

Click Finish, and we’ll save all the information you’ve provided. If you don’t have your Prescription Insurance Card information, simply select Skip This Step and contact ENBREL Support ® to complete your enrollment.

Please try again, or contact the ENBREL® SupportPlus team at 1-888-4ENBREL.

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Enbrel® Co-Pay Card

Congratulations! Based on the information you provided, you are eligible for this card. You should receive your activated card in 2-3 business days. Please have this card ready when paying for your ENBREL medication.

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Thank you for your interest in the Enbrel® Co-Pay Card

It appears that we need to gather more information from you.

Please contact the ENBREL® SupportPlus team at 1-888-4ENBREL (1-888-436-2735) for further assistance. Our team is ready to help Monday-Sunday, 8 AM-11 PM ET.

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Thank you for your interest in the Enbrel® Co-Pay Card

Based on the information you provided, we're unable to complete your enrollment online.

Please contact the ENBREL® SupportPlus team at 1-888-4ENBREL (1-888-436-2735) for further assistance. Our team is ready to help Monday-Sunday, 8 AM-11 PM ET.

Enbrel phone icon

You indicated you have government-provided insurance

Based on the information you provided, we’re unable to complete your enrollment online.

Our team of Medicare Solutions Specialists know about Medicare and can help you understand your Medicare coverage, including the donut hole and anticipating annual out-of-pocket costs for ENBREL. We can also help you find answers to other questions you may have about ENBREL and your Medicare Part D or Medicaid plan, and more.

Please contact the ENBREL® SupportPlus team at 1-888-4ENBREL (1-888-436-2735) for further assistance. Our team is ready to help Monday-Sunday, 8 AM-11 PM ET.

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You've indicated you don't currently have insurance

The Amgen Safety Net Foundation is an independent, nonprofit, patient assistance program that helps patients with financial need gain access to ENBREL at no cost.

Learn More
Enbrel question icon

You indicated you're not sure of your insurance coverage

Please contact the ENBREL® SupportPlus team at 1-888-4ENBREL (1-888-436-2735) for further assistance. Our team is ready to help Monday-Sunday, 8 AM-11 PM ET.

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Download the Embark® App for free today and get financial support information, medication reminders, injection site tracking and more—all in the palm of your hand.

Simply scan this code with your camera.

embark app

Following are the resources and services you have selected:

Establishing Your ENBREL Routine

Below are the resources you selected to help you get started with your ENBREL treatment routine. And remember, if you have any questions along the way, ENBREL® SupportPlus is just a call away at 1-888-4-ENBREL.

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Enbrel Mini® Cartridge with AutoTouch® Autoinjector

Watch this video to supplement the information you got from your doctor on how to use the Enbrel Mini® cartridge with AutoTouch® autoinjector. This video does not replace the Instructions for Use, which cover everything you need to know about how to use the Enbrel Mini® cartridge with AutoTouch® autoinjector.

Enbrel Mini® cartridge with AutoTouch® autoinjector Instructions for Use Medication Guide
autoinjector autoinjector

SureClick® Autoinjector Video

Watch the video below to see how the SureClick® Autoinjector works.

SureClick® Autoinjector Instructions for Use Medication Guide
pfs pfs

Prefilled Syringe

Watch this short video to see how the prefilled syringe works.

Prefilled syringe Instructions for Use Medication Guide
single dose vial single dose vial

Single-Dose Vial

A ready-to-use formulation. Review the instructions for Use, which cover everything you need to know about how to use the single-dose vial.

Single-dose vial Instructions for Use Medication Guide
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ENBREL supplement injection demo videos

Learn more about different injection options and watch demonstration videos to see how each device works.

Watch the videos
nurse partner

ENBREL Nurse Partners

ENBREL Nurse Partners™ provide one-on-one support to help establish your ENBREL treatment routine.

  • One-on-one supplemental injection training
  • Information about available ENBREL® SupportPlus services
  • Information about ENBREL and your condition

ENBREL Nurse Partners™ are nurses by training, but they are not part of your treatment team or an extension of your doctor’s office. ENBREL Nurse Partners™ do not inject patients with ENBREL. You will be referred to your doctor’s office for clinical advice.

One of our ENBREL Nurse Partners™ will be reaching out to you within 1-2 business days.

Enbrel guide

My ENBREL Guide

You will receive your copy of My ENBREL Guide via mail in 3-5 business days. In the meantime, you can download an electronic copy.

Download
Statwise

STATWISE™ Symptom Tracker

To help answer the question, “Is ENBREL working for me?” we’ve developed STATWISE™—a simple-to-use text message program that may help you to see signs you might be missing.

Take a few moments to respond to 3 text messages every day and rate your symptoms. A STATWISE™ symptom report capturing your personal experience will be generated automatically every 2 weeks that may help you understand your progress with ENBREL and share your results with your doctor or loved ones.

For detailed instructions, go to the Instructions & FAQs page.

Additional Resources

Condition management guide

ENBREL Condition Management Guide

In this guide, you’ll get information about what you might expect during your first 3 months of treatment with ENBREL. You’ll also find questions that can help you and your doctor identify treatment goals and ways to track your progress.

Download Download Download Download
+ See More

Important Safety Information

What is the most important information I should know about ENBREL?

ENBREL is a medicine that affects your immune

ENBREL is a medicine that affects your immune system. ENBREL can lower the ability of your immune system to fight infections. Serious infections
have happened in patients taking ENBREL. These infections include tuberculosis (TB) and infections caused by viruses, fungi, or bacteria that have

 
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Prescription Enbrel® (etanercept) is taken (given) by injection.

Important Safety Information

What is the most important information I should know about ENBREL?

ENBREL is a medicine that affects your immune system. ENBREL can lower the ability of your immune system to fight infections. Serious infections have happened in patients taking ENBREL. These infections include tuberculosis (TB) and infections caused by viruses, fungi, or bacteria that have spread throughout the body. Some patients have died from these infections. Your healthcare provider should test you for TB before you take ENBREL and monitor you closely for TB before, during, and after ENBREL treatment, even if you have tested negative for TB.

There have been some cases of unusual cancers, some resulting in death, reported in children and teenage patients who started using tumor necrosis factor (TNF) blockers before 18 years of age. Also, for children, teenagers, and adults taking TNF blockers, including ENBREL, the chances of getting lymphoma or other cancers may increase. Patients with RA may be more likely to get lymphoma.

Before starting ENBREL, tell your healthcare provider if you:

  • Have any existing medical conditions
  • Are taking any medicines, including herbals
  • Think you have, are being treated for, have signs of, or are prone to infection. You should not start taking ENBREL if you have any kind of infection, unless your healthcare provider says it is okay
  • Have any open cuts or sores
  • Have diabetes, HIV, or a weak immune system
  • Have TB or have been in close contact with someone who has had TB
  • Were born in, lived in, or traveled to countries where there is more risk for getting TB. Ask your healthcare provider if you are not sure
  • Live, have lived in, or traveled to certain parts of the country (such as, the Ohio and Mississippi River valleys, or the Southwest) where there is a greater risk for certain kinds of fungal infections, such as histoplasmosis. These infections may develop or become more severe if you take ENBREL. If you don’t know if these infections are common in the areas you’ve been to, ask your healthcare provider
  • Have or have had hepatitis B
  • Have or have had heart failure
  • Develop symptoms such as persistent fever, bruising, bleeding, or paleness while taking ENBREL
  • Use the medicine Kineret (anakinra), Orencia (abatacept), or Cytoxan (cyclophosphamide)
  • Are taking anti-diabetic medicines
  • Have, have had, or develop a serious nervous disorder, seizures, any numbness or tingling, or a disease that affects your nervous system such as multiple sclerosis or Guillain-Barré syndrome
  • Are scheduled to have surgery
  • Have recently received or are scheduled for any vaccines. All vaccines should be brought up-to-date before starting ENBREL. Patients taking ENBREL should not receive live vaccines.
  • Are allergic to rubber or latex
  • Are pregnant, planning to become pregnant, or breastfeeding
  • Have been around someone with chicken pox

What are the possible side effects of ENBREL?

ENBREL can cause serious side effects including: New infections or worsening of infections you already have; hepatitis B can become active if you already have had it; nervous system problems, such as multiple sclerosis, seizures, or inflammation of the nerves of the eyes; blood problems (some fatal); new or worsening heart failure; new or worsening psoriasis; allergic reactions; autoimmune reactions, including a lupus-like syndrome and autoimmune hepatitis.

Common side effects include: Injection site reactions and upper respiratory infections (sinus infections).

In general, side effects in children were similar in frequency and type as those seen in adult patients. The types of infections reported were generally mild and similar to those usually seen in children.

These are not all the side effects with ENBREL. Tell your healthcare provider about any side effect that bothers you or does not go away.

If you have any questions about this information, be sure to discuss them with your healthcare provider. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Please see Prescribing Information and Medication Guide.

Indications

Moderate to Severe Rheumatoid Arthritis (RA)

ENBREL is indicated for reducing signs and symptoms, keeping joint damage from getting worse, and improving physical function in patients with moderately to severely active rheumatoid arthritis. ENBREL can be taken with methotrexate or used alone.

Psoriatic Arthritis

ENBREL is indicated for reducing signs and symptoms, keeping joint damage from getting worse, and improving physical function in patients with psoriatic arthritis. ENBREL can be used with or without methotrexate.

Moderate to Severe Plaque Psoriasis

ENBREL is indicated for chronic moderate to severe plaque psoriasis (PsO) in children 4 years and older and adults who may benefit from taking injections or pills (systemic therapy) or phototherapy (ultraviolet light).

Ankylosing Spondylitis (AS)

ENBREL is indicated for reducing signs and symptoms in patients with active ankylosing spondylitis.

Moderately to Severely Active Polyarticular Juvenile Idiopathic Arthritis (JIA)

ENBREL is indicated for reducing signs and symptoms of moderately to severely active polyarticular juvenile idiopathic arthritis (JIA) in children ages 2 years and older.

The Bluetooth® word mark and logos are registered trademarks owned by Bluetooth SIG, Inc. and any use of such marks by Amgen is under license.

References: 1. Parsabiv® (etelcalcetide) prescribing information, Amgen. 2. Data on file, Amgen; [Summary of Clinical Efficacy; 2015]. 3. Alexander ST, et al. Mol Pharmacol. 2015;88:853-865. 4. Data on file, Amgen; [Report R20130052, 2014]. 5. Chen P, et al. CPT Pharmacometrics Syst Pharmacol. 2016;5:484-494. 6. Sensipar® (cinacalcet) prescribing information, Amgen. 7. Ma JN, et al. J Pharmacol Exp Ther. 2011;337:275-284.
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