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Indications

ENBREL is indicated for reducing signs and symptoms, keeping joint damage from getting worse, and improving physical function in patients with moderately to severely active rheumatoid arthritis. ENBREL can be taken with methotrexate or used alone. Read More

ENBREL is indicated for chronic moderate to severe plaque psoriasis (PsO) in children 4 years and older and adults who may benefit from taking injections or pills (systemic therapy) or phototherapy (ultraviolet light). 
ENBREL is indicated for reducing signs and symptoms, keeping joint damage from getting worse, and improving physical function in patients with psoriatic arthritis. ENBREL can be used with or without methotrexate.
ENBREL is indicated for reducing signs and symptoms in patients with active ankylosing spondylitis. 
ENBREL is indicated for reducing signs and symptoms of moderately to severely active polyarticular juvenile idiopathic arthritis (JIA) in children ages 2 years and older. Close

ENBREL® SupportPlus and Resources

Starting a biologic medicine can be different from other treatments you have used. So you may have a lot of questions. ENBREL® SupportPlus was created to give you answers and more about taking ENBREL. ENBREL® SupportPlus offers services and resources designed to help patients like you more easily start and stay on your treatment routine. Take the next step and enroll in ENBREL® SupportPlus today.

Let us help you.

  • I’m new to Enbrel
  • I’m exploring my financial options
  • I have questions about using specialty pharmacies and getting my Enbrel
  • I want help administering my Enbrel treatment and establishing a routine
  • I’m ready to evaluate my progress
  • I’m looking for more resources
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I’m New to ENBREL

With the help of patients who have been through this experience before, ENBREL® SupportPlus has developed these resources to make it easier to get started on ENBREL.

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Enroll in ENBREL® SupportPlus

Enroll in ENBREL® SupportPlus to access support services, tools, resources, and financial support options and information that can help you start and stay on ENBREL as prescribed. For more information about the program, click the download button below for a brochure.

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Meet the Embark® App

The Embark® App has been designed to support your ENBREL experience. You'll get access to ENBREL® SupportPlus, medication reminders, injection site tracking and more—all in the palm of your hand. Click the button below to download it for free today.

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How ENBREL® SupportPlus
Can Help You

We've created this short video to give you an overview of how ENBREL® SupportPlus can help you get started with your ENBREL prescription.

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My ENBREL Guide

My ENBREL Guide covers the most important things you need to know after your doctor prescribes ENBREL. This includes information about the potential benefits and risks of treatment, applying for financial support, working with your pharmacy, setting up your injection routine, and traveling with ENBREL.

Once you start treatment, My ENBREL Guide can help you track your progress as you notice any improvements or changes. That way, you’re prepared for your next doctor’s appointment when you’ll discuss how ENBREL is working for you.

Get your copy of My ENBREL Guide here, or by enrolling in ENBREL® SupportPlus today.

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ENBREL Patient Roadmap

Starting a biologic can be different from other treatments. The ENBREL Patient Roadmap provides a step-by-step guide to help you confidently initiate and establish a treatment routine. Bonus: It’s already included in your comprehensive My ENBREL Guide mentioned earlier.

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Switching to ENBREL from another self-injectable? Check out this guide.

Contact ENBREL® SupportPlus

Our support specialists can answer questions about getting started with your ENBREL treatment. For one-on-one assistance, call 1-888-4ENBREL (1-888-436-2735), Monday through Friday, from 8 AM to 8 PM ET.

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I’m exploring my financial options

The first questions many new ENBREL patients have are about the cost of treatment. Regardless of your income level, your current financial situation, or the type of insurance you have, ENBREL® SupportPlus has insurance specialists who are ready to help. Learn more about Paying for ENBREL.

Commercially insured

If you are commercially insured (sometimes referred to as having private insurance, or insurance you receive from your employer), you may pay as little as $0 per month with the Enbrel® Co-Pay Card program* available online through ENBREL® SupportPlus or by calling 1-888-4ENBREL (1-888-436-2735). Eligibility for the Enbrel® Co-Pay Card is not based on income, so be prepared by applying for the co-pay card now, so you have it when you need it.

 

*Eligibility criteria and program limits apply. Click “ENROLL NOW” to learn more.

Government insured (Medicare/Medicaid)

Our team of Medicare Solutions specialists can help you understand your Medicare coverage, including the donut hole and anticipating annual out-of-pocket costs for ENBREL. They can also screen for Extra Help (Low Income Subsidy) eligibility, or provide referral assistance to third-party nonprofit foundations.* To learn more, call ENBREL® SupportPlus at 1-888-4ENBREL (1-888-436-2735).

*Support provided through independent charitable patient assistance programs; program eligibility is based on the charity’s criteria. ENBREL® SupportPlus has no control over independent, third-party programs and provides referrals as a courtesy only.

Uninsured or unsure

ENBREL® SupportPlus can put you in touch with the Amgen Safety Net Foundation—a nonprofit patient assistance program sponsored by Amgen that helps qualifying patients access Amgen medicines at no cost.

To learn more, call ENBREL® SupportPlus at 1-888-4ENBREL (1-888-436-2735).

Why enroll in ENBREL® SupportPlus now?

Very soon you'll receive a call from a Specialty Pharmacy to arrange for delivery and to collect payment for your first prescription of ENBREL. Before they call, it's important to know all the financial options that may help lower your out-of-pocket prescription costs. Enroll today to speak with a Welcome Specialist.

For more information about the program, check out the brochure below.

Meet the Embark® App

The Embark® App has been designed to support your ENBREL experience. You'll get access to ENBREL® SupportPlus, medication reminders, injection site tracking and more-all in the palm of your hand. Click the button below to download it for free today.

How Can ENBREL® SupportPlus Help You Afford ENBREL

Watch this video to help you understand your financial support options—including the Enbrel® Co-Pay Card.

Eligibility criteria and program limits apply.

My ENBREL Guide

Within the pages of this comprehensive guide, you’ll find information about how ENBREL® SupportPlus can help connect you with financial support options that will best suit your situation. Get your copy of My ENBREL Guide here, or by enrolling in ENBREL® SupportPlus today.

Contact ENBREL® SupportPlus

For more information about financial support options, contact ENBREL® SupportPlus. Our financial support specialists can answer any questions you may have about financial support options. For one-on-one assistance, call 1-888-4ENBREL (1-888-436-2735), Monday through Friday, from 8 AM to 8 PM ET.


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I have questions about using specialty pharmacies and getting my Enbrel

A Specialty Pharmacy is a type of pharmacy that distributes more complex medications like yours that may require special storage or handling, such as refrigeration. ENBREL is one of those medications.

Getting Your ENBREL Through the Specialty Pharmacy

We've created this short video, which includes information on using a specialty pharmacy, to give you an overview of some important things to know as you get started.

Specialty Pharmacy

My ENBREL Guide

If you need additional information about how to get your ENBREL medication, ENBREL® SupportPlus has created this clear, step-by-step guide to help you successfully get started on ENBREL. Consider it your insider’s guide, explaining things like Specialty Pharmacies and how they work with your doctor and insurance to fill your Enbrel prescription. Get your copy of My ENBREL Guide here, or by enrolling in ENBREL® SupportPlus today.

Enroll in ENBREL® SupportPlus

If you still have questions about Specialty Pharmacies and how they work, we have the answers. Just enroll in ENBREL® SupportPlus to speak with one of our Welcome Specialists.

Contact ENBREL® SupportPlus

Our support specialists can answer questions about your specialty pharmacy. For one-on-one assistance, call 1-888-4ENBREL (1-888-436-2735), Monday through Friday, from 8 AM to 8 PM ET.

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I want help administering my Enbrel treatment and establishing a routine

At this point, you’ve likely scheduled the delivery of your ENBREL prescription. While you wait for it to arrive, we can help you begin planning an injection routine that fits your schedule. We have a number of ENBREL resources to help you get started.

ENBREL Nurse Partners™*

By enrolling in ENBREL® SupportPlus, you can access our ENBREL Nurse Partners™ program. ENBREL Nurse Partners™ can provide you with one-on-one support at home, by phone, or video chat. You can also get one-on-one supplemental injection support. Talk to an ENBREL Nurse Partner™ if you need information about ENBREL and the available ENBREL® SupportPlus services.

Watch this video for an overview of the support and resources ENBREL Nurse Partners™ can provide.

*ENBREL Nurse Partners™ are nurses by training, but they are not part of your treatment team or an extension of your doctor’s office. ENBREL Nurse Partners™ do not inject patients with ENBREL. You will be referred to your doctor’s office for clinical advice.

AutoTouch® Autoinjector Help

Enbrel Mini® cartridge with AutoTouch® and AutoTouch Connect® autoinjector demonstration videos, troubleshooting, supplemental resources and more.

Injection Demonstration Videos

If you’d like to see how the actual injection process works, have a look at these quick demonstration videos that supplement the information you got from your doctor on how to inject ENBREL. These videos show how to take your ENBREL injections using your prescribed ENBREL device but they do not replace the Instructions for Use. Please consult the Instructions for Use when taking ENBREL. These instructions cover everything you need to know about how to use ENBREL.

Enroll in ENBREL® SupportPlus

Enrolling opens up a range of support services, including ENBREL Nurse Partners™.

Meet the Embark® App

The Embark® App has been designed to support your ENBREL experience. You'll get access to ENBREL® SupportPlus, medication reminders, injection site tracking and more—all in the palm of your hand. Click the button below to download it for free today.

My ENBREL Guide

For patients like you who are ready to establish their ENBREL treatment routines, ENBREL® SupportPlus has created this clear, step-by-step guide to help you successfully get started and stay on ENBREL as prescribed. It’s loaded with tips, instructions, suggestions, and so many other things that will help you establish an ENBREL treatment routine that’s right for you. Get your copy of My ENBREL Guide here, or by enrolling in ENBREL® SupportPlus today.

Storage & Travel

Treatment with ENBREL means traveling can be something to look forward to again. But traveling doesn’t mean you need to miss any of your ENBREL treatments. Check out these 6 tips on traveling with and storing Enbrel by reading through our brochure or by visiting our travel & storage page.

Contact an ENBREL Nurse Partner™

For one-on-one support, call 1-888-4ENBREL (1-888-436-2735), 5 days a week, 8 AM–8 PM (ET).

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I’m ready to evaluate my progress

If you’ve started ENBREL, you’re probably wondering whether ENBREL is working and when you’ll start to see results. Because of every patient is unique, it may take time to pinpoint your results. ENBREL® SupportPlus has resources to help you understand what to expect when starting treatment and tools to help you track your symptoms along the way.

STATWISE™ Symptom Tracker

If you have moderate to severe rheumatoid arthritis or psoriatic arthritis, the simple-to-use STATWISE™ text message program may help you answer the question, "Is ENBREL working for me?" It may help you to see the signs of improvement you might be missing.

Meet the Embark® App

The Embark® App has been designed to support your ENBREL experience. You'll get access to ENBREL® SupportPlus, medication reminders, injection site tracking and more-all in the palm of your hand. Click the button below to download it for free today.

Condition Management Guide

In this guide, you’ll get information about what you might expect during your first 3 months of treatment with ENBREL. Download the Condition Management Guide specific to your diagnosis.

My ENBREL Guide

It’s important to stay motivated while you wait to see how ENBREL may work for you. My ENBREL Guide helps you understand what you can expect when starting treatment. The guide also has useful tools to track your symptoms and tips on how you can take control of your treatment routine. Get your copy of My ENBREL Guide here, or by enrolling in ENBREL® SupportPlus today.

Contact ENBREL® SupportPlus

Our support specialists can answer your questions about tracking and evaluating your ENBREL treatment. For one-on-one assistance, call 1-888-4ENBREL (1-888-436-2735), Monday through Friday, from 8 AM to 8 PM ET.

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I’m looking for more resources

You may be eager to see how well ENBREL may work for you and when you can expect to see results. So, we’ve created this section of resources and information to help you stay positive during this time and remain focused on the things you can control.

Enroll in ENBREL® SupportPlus

Enroll in ENBREL® SupportPlus

Enroll in ENBREL® SupportPlus to access support services, tools, resources, financial support options and information that can help you start and stay on ENBREL. For more information about the program, watch the video or click the download button below for a brochure.

Meet the Embark® App

embark app

Meet the Embark® App

The Embark® App has been designed to support your ENBREL experience. You'll get access to ENBREL® SupportPlus, medication reminders, injection site tracking and more—all in the palm of your hand. Click the button below to download it for free today.

AutoTouch® Autoinjector Help

AutoTouch® Autoinjector Help

Enbrel Mini® cartridge with AutoTouch® and AutoTouch Connect® autoinjector demonstration videos, troubleshooting, supplemental resources and more.

Financial Resources Options

Financial Resources Options

The first questions many new ENBREL patients have are about the cost of treatment. Regardless of your income level, your current financial situation, or the type of insurance you have, ENBREL® SupportPlus has financial support specialists who are ready to help.

My ENBREL Guide

My ENBREL Guide

With the help of patients just like you, ENBREL® SupportPlus has created this clear, step-by-step guide to help you successfully get started on ENBREL.

ENBREL Patient Roadmap

ENBREL Patient Roadmap

Starting a biologic can be different from other treatments. The ENBREL Patient Roadmap provides a step-by-step guide to help you confidently initiate and establish a treatment routine.

Switching to ENBREL from another self-injectable? Check out this guide.

STATWISE™ Symptom Tracker

STATWISE™ Symptom Tracker

If you have moderate to severe rheumatoid arthritis or psoriatic arthritis, the simple-to-use STATWISE™ text message program may help you track key symptoms to let you know how you're doing while you're on ENBREL.

ENBREL Nurse Partners™*

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ENBREL Nurse Partners™*

ENBREL Nurse Partners™ can provide you with one-on-one support at home, by phone, or video chat. You can also get one-on-one supplemental injection support. Talk to an ENBREL Nurse Partner™ if you need information about ENBREL and the available ENBREL® SupportPlus services.

*ENBREL Nurse Partners™ are nurses by training, but they are not part of your treatment team or an extension of your doctor’s office. ENBREL Nurse Partners™ do not inject patients with ENBREL. You will be referred to your doctor’s office for clinical advice.

What Is Prior Authorization?

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What Is Prior Authorization?

After you’ve been prescribed ENBREL, a specialty pharmacy will be notified of your prescription by your doctor, who will work with your insurance provider to confirm coverage and prescription costs.

Supplemental Injection Support

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Supplemental Injection Support

Whether you’re feeling comfortable with injecting ENBREL or are a little nervous about the process, knowing how to inject correctly is a key part of taking ENBREL. ENBREL® SupportPlus has a variety of resources available to help supplement the training you received from your doctor.

Taking ENBREL

Taking ENBREL

You will be trained by your HCP on how to inject ENBREL. These demonstration videos can provide additional help in understanding your prescribed ENBREL device.

Condition Management Guide

Condition Management Guide

In this guide, you’ll get information about what you might expect during your first 3 months of treatment with ENBREL. Download the Condition Management Guide specific to your diagnosis.

Enbrel Mini® Cartridge with AutoTouch® Autoinjector

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Enbrel Mini® Cartridge with AutoTouch® Autoinjector

It’s an injection experience designed with you in mind. Learn more about the Enbrel Mini® cartridge with AutoTouch® autoinjector.

Joint Damage Simulator

Joint Damage Simulator

Joint pain could actually be a sign of permanent joint damage. Use the Joint Damage Simulator to see how joint damage can get worse over time.

Contact ENBREL® SupportPlus

Our support specialists can answer questions. For one-on-one assistance, call 1-888-4ENBREL (1-888-436-2735), Monday through Friday, from 8 AM to 8 PM ET.

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ENBREL® SupportPlus Enrollment

It’s a simple way to sign up for resources that can help you get started with ENBREL.

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Important Safety Information

What is the most important information I should know about ENBREL?

ENBREL is a medicine that affects your immune

ENBREL is a medicine that affects your immune system. ENBREL can lower the ability of your immune system to fight infections. Serious infections
have happened in patients taking ENBREL. These infections include tuberculosis (TB) and infections caused by viruses, fungi, or bacteria that have

 
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Prescription Enbrel® (etanercept) is taken (given) by injection.

Important Safety Information

What is the most important information I should know about ENBREL?

ENBREL is a medicine that affects your immune system. ENBREL can lower the ability of your immune system to fight infections. Serious infections have happened in patients taking ENBREL. These infections include tuberculosis (TB) and infections caused by viruses, fungi, or bacteria that have spread throughout the body. Some patients have died from these infections. Your healthcare provider should test you for TB before you take ENBREL and monitor you closely for TB before, during, and after ENBREL treatment, even if you have tested negative for TB.

There have been some cases of unusual cancers, some resulting in death, reported in children and teenage patients who started using tumor necrosis factor (TNF) blockers before 18 years of age. Also, for children, teenagers, and adults taking TNF blockers, including ENBREL, the chances of getting lymphoma or other cancers may increase. Patients with RA may be more likely to get lymphoma.

Before starting ENBREL, tell your healthcare provider if you:

  • Have any existing medical conditions
  • Are taking any medicines, including herbals
  • Think you have, are being treated for, have signs of, or are prone to infection. You should not start taking ENBREL if you have any kind of infection, unless your healthcare provider says it is okay
  • Have any open cuts or sores
  • Have diabetes, HIV, or a weak immune system
  • Have TB or have been in close contact with someone who has had TB
  • Were born in, lived in, or traveled to countries where there is more risk for getting TB. Ask your healthcare provider if you are not sure
  • Live, have lived in, or traveled to certain parts of the country (such as, the Ohio and Mississippi River valleys, or the Southwest) where there is a greater risk for certain kinds of fungal infections, such as histoplasmosis. These infections may develop or become more severe if you take ENBREL. If you don’t know if these infections are common in the areas you’ve been to, ask your healthcare provider
  • Have or have had hepatitis B
  • Have or have had heart failure
  • Develop symptoms such as persistent fever, bruising, bleeding, or paleness while taking ENBREL
  • Use the medicine Kineret (anakinra), Orencia (abatacept), or Cytoxan (cyclophosphamide)
  • Are taking anti-diabetic medicines
  • Have, have had, or develop a serious nervous disorder, seizures, any numbness or tingling, or a disease that affects your nervous system such as multiple sclerosis or Guillain-Barré syndrome
  • Are scheduled to have surgery
  • Have recently received or are scheduled for any vaccines. All vaccines should be brought up-to-date before starting ENBREL. Patients taking ENBREL should not receive live vaccines.
  • Are allergic to rubber or latex
  • Are pregnant, planning to become pregnant, or breastfeeding
  • Have been around someone with chicken pox

What are the possible side effects of ENBREL?

ENBREL can cause serious side effects including: New infections or worsening of infections you already have; hepatitis B can become active if you already have had it; nervous system problems, such as multiple sclerosis, seizures, or inflammation of the nerves of the eyes; blood problems (some fatal); new or worsening heart failure; new or worsening psoriasis; allergic reactions; autoimmune reactions, including a lupus-like syndrome and autoimmune hepatitis.

Common side effects include: Injection site reactions and upper respiratory infections (sinus infections).

In general, side effects in children were similar in frequency and type as those seen in adult patients. The types of infections reported were generally mild and similar to those usually seen in children.

These are not all the side effects with ENBREL. Tell your healthcare provider about any side effect that bothers you or does not go away.

If you have any questions about this information, be sure to discuss them with your healthcare provider. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Please see Prescribing Information and Medication Guide.

Indications

Moderate to Severe Rheumatoid Arthritis (RA)

ENBREL is indicated for reducing signs and symptoms, keeping joint damage from getting worse, and improving physical function in patients with moderately to severely active rheumatoid arthritis. ENBREL can be taken with methotrexate or used alone.

Psoriatic Arthritis

ENBREL is indicated for reducing signs and symptoms, keeping joint damage from getting worse, and improving physical function in patients with psoriatic arthritis. ENBREL can be used with or without methotrexate.

Moderate to Severe Plaque Psoriasis

ENBREL is indicated for chronic moderate to severe plaque psoriasis (PsO) in children 4 years and older and adults who may benefit from taking injections or pills (systemic therapy) or phototherapy (ultraviolet light).

Ankylosing Spondylitis (AS)

ENBREL is indicated for reducing signs and symptoms in patients with active ankylosing spondylitis.

Moderately to Severely Active Polyarticular Juvenile Idiopathic Arthritis (JIA)

ENBREL is indicated for reducing signs and symptoms of moderately to severely active polyarticular juvenile idiopathic arthritis (JIA) in children ages 2 years and older.

The Bluetooth® word mark and logos are registered trademarks owned by Bluetooth SIG, Inc. and any use of such marks by Amgen is under license.

References: 1. Parsabiv® (etelcalcetide) prescribing information, Amgen. 2. Data on file, Amgen; [Summary of Clinical Efficacy; 2015]. 3. Alexander ST, et al. Mol Pharmacol. 2015;88:853-865. 4. Data on file, Amgen; [Report R20130052, 2014]. 5. Chen P, et al. CPT Pharmacometrics Syst Pharmacol. 2016;5:484-494. 6. Sensipar® (cinacalcet) prescribing information, Amgen. 7. Ma JN, et al. J Pharmacol Exp Ther. 2011;337:275-284.
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