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Indications

ENBREL is indicated for reducing signs and symptoms, keeping joint damage from getting worse, and improving physical function in patients with moderately to severely active rheumatoid arthritis. ENBREL can be taken with methotrexate or used alone. Read More

ENBREL is indicated for chronic moderate to severe plaque psoriasis (PsO) in children 4 years and older and adults who may benefit from taking injections or pills (systemic therapy) or phototherapy (ultraviolet light). 
ENBREL is indicated for reducing signs and symptoms, keeping joint damage from getting worse, and improving physical function in patients with psoriatic arthritis. ENBREL can be used with or without methotrexate.
ENBREL is indicated for reducing signs and symptoms in patients with active ankylosing spondylitis. 
ENBREL is indicated for reducing signs and symptoms of moderately to severely active polyarticular juvenile idiopathic arthritis (JIA) in children ages 2 years and older. Close

Enbrel Mini® Cartridge with AutoTouch® Autoinjector

  • OVERVIEW
  • FEATURES
  • Help

Enbrel Mini® single-dose prefilled cartridge with AutoTouch® reusable autoinjector

The Enbrel Mini® cartridge with AutoTouch® autoinjector is a reusable autoinjector.* It is designed with patients in mind, with a comfortable gray finger grip, an easy-to-press status button, and a needle designed to remain hidden throughout the injection process. It also has an injection progress bar and lights and sounds that help patients confirm the injection process is complete. 

Watch this video and learn even more about the Enbrel Mini® cartridge with AutoTouch® autoinjector. 

*Reusable for up to 2 years or 130 injections, whichever comes first.

 

It is important that you thoroughly review the patient Instructions for Use. These instructions cover everything you need to know about how to use the Enbrel Mini® single-dose prefilled cartridge with AutoTouch® autoinjector. The information on this website does not replace the patient Instructions for Use. Please contact your healthcare provider if you have any questions.

 

The Enbrel Mini® single-dose prefilled cartridge with AutoTouch® autoinjector is not for use in children (ages 4-17) with moderate to severe plaque psoriasis (PsO) or children with juvenile idiopathic arthritis (JIA) who weigh less than 138 pounds.

Enbrel Mini® cartridge with AutoTouch® autoinjector features innovations designed with patients in mind

A light press
of the start button
begins the injection

The ergonomic,
easy-to-grip design
was inspired by
common household
objects

Sound switch gives
you the option to hear
sounds that help
guide your injection

On the progress bar,
the LED indicators
show the progress
of the injection from
start to finish-
letting you know the
injection is complete

Select from
3 injection-speed
options to find the
one that’s most
comfortable for you

Device activates on
contact with skin,
illuminating the green
“start button” and
letting you know the
device is ready to inject

Hidden-needle design

On the progress bar, the LED indicators show the progress of the injection from start to finish—letting you know the injection is complete

Select from 3 injection-speed options to find the one that’s most comfortable for you

Hidden-needle design

A light press of the start button begins the injection

The ergonomic, easy-to-grip design was inspired by common household objects

Sound switch gives you the option to hear sounds that help guide your injection

Device activates on contact with skin, illuminating the green “start button” and letting you know the device is ready to inject

Let’s figure this out—together

The Enbrel Mini® cartridge with AutoTouch® autoinjector makes a chime sound, lights the status button red, and displays an error symbol if there is a problem. If this happens with your device, you can learn more about what to do by watching the videos below.

Flashing red status button

Low or dead battery

Needle exposure

Too hot or too cold

Device symbol error

Device failure

Inserting cartridge

It is important that you thoroughly review the patient Instructions for Use. These instructions cover everything you need to know about how to use the Enbrel Mini® single-dose prefilled cartridge with AutoTouch® autoinjector. The information on this website does not replace the patient Instructions for Use. Please contact your healthcare provider if you have any questions.

+ See More

Important Safety Information

What is the most important information I should know about ENBREL?

ENBREL is a medicine that affects your immune

ENBREL is a medicine that affects your immune system. ENBREL can lower the ability of your immune system to fight infections. Serious infections
have happened in patients taking ENBREL. These infections include tuberculosis (TB) and infections caused by viruses, fungi, or bacteria that have

 
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Prescription Enbrel® (etanercept) is taken (given) by injection.

Important Safety Information

What is the most important information I should know about ENBREL?

ENBREL is a medicine that affects your immune system. ENBREL can lower the ability of your immune system to fight infections. Serious infections have happened in patients taking ENBREL. These infections include tuberculosis (TB) and infections caused by viruses, fungi, or bacteria that have spread throughout the body. Some patients have died from these infections. Your healthcare provider should test you for TB before you take ENBREL and monitor you closely for TB before, during, and after ENBREL treatment, even if you have tested negative for TB.

There have been some cases of unusual cancers, some resulting in death, reported in children and teenage patients who started using tumor necrosis factor (TNF) blockers before 18 years of age. Also, for children, teenagers, and adults taking TNF blockers, including ENBREL, the chances of getting lymphoma or other cancers may increase. Patients with RA may be more likely to get lymphoma.

Before starting ENBREL, tell your healthcare provider if you:

  • Have any existing medical conditions
  • Are taking any medicines, including herbals
  • Think you have, are being treated for, have signs of, or are prone to infection. You should not start taking ENBREL if you have any kind of infection, unless your healthcare provider says it is okay
  • Have any open cuts or sores
  • Have diabetes, HIV, or a weak immune system
  • Have TB or have been in close contact with someone who has had TB
  • Were born in, lived in, or traveled to countries where there is more risk for getting TB. Ask your healthcare provider if you are not sure
  • Live, have lived in, or traveled to certain parts of the country (such as, the Ohio and Mississippi River valleys, or the Southwest) where there is a greater risk for certain kinds of fungal infections, such as histoplasmosis. These infections may develop or become more severe if you take ENBREL. If you don’t know if these infections are common in the areas you’ve been to, ask your healthcare provider
  • Have or have had hepatitis B
  • Have or have had heart failure
  • Develop symptoms such as persistent fever, bruising, bleeding, or paleness while taking ENBREL
  • Use the medicine Kineret (anakinra), Orencia (abatacept), or Cytoxan (cyclophosphamide)
  • Are taking anti-diabetic medicines
  • Have, have had, or develop a serious nervous disorder, seizures, any numbness or tingling, or a disease that affects your nervous system such as multiple sclerosis or Guillain-Barré syndrome
  • Are scheduled to have surgery
  • Have recently received or are scheduled for any vaccines. All vaccines should be brought up-to-date before starting ENBREL. Patients taking ENBREL should not receive live vaccines.
  • Are allergic to rubber or latex
  • Are pregnant, planning to become pregnant, or breastfeeding
  • Have been around someone with chicken pox

What are the possible side effects of ENBREL?

ENBREL can cause serious side effects including: New infections or worsening of infections you already have; hepatitis B can become active if you already have had it; nervous system problems, such as multiple sclerosis, seizures, or inflammation of the nerves of the eyes; blood problems (some fatal); new or worsening heart failure; new or worsening psoriasis; allergic reactions; autoimmune reactions, including a lupus-like syndrome and autoimmune hepatitis.

Common side effects include: Injection site reactions and upper respiratory infections (sinus infections).

In general, side effects in children were similar in frequency and type as those seen in adult patients. The types of infections reported were generally mild and similar to those usually seen in children.

These are not all the side effects with ENBREL. Tell your healthcare provider about any side effect that bothers you or does not go away.

If you have any questions about this information, be sure to discuss them with your healthcare provider. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Please see Prescribing Information and Medication Guide.

Indications

Moderate to Severe Rheumatoid Arthritis (RA)

ENBREL is indicated for reducing signs and symptoms, keeping joint damage from getting worse, and improving physical function in patients with moderately to severely active rheumatoid arthritis. ENBREL can be taken with methotrexate or used alone.

Psoriatic Arthritis

ENBREL is indicated for reducing signs and symptoms, keeping joint damage from getting worse, and improving physical function in patients with psoriatic arthritis. ENBREL can be used with or without methotrexate.

Moderate to Severe Plaque Psoriasis

ENBREL is indicated for chronic moderate to severe plaque psoriasis (PsO) in children 4 years and older and adults who may benefit from taking injections or pills (systemic therapy) or phototherapy (ultraviolet light).

Ankylosing Spondylitis (AS)

ENBREL is indicated for reducing signs and symptoms in patients with active ankylosing spondylitis.

Moderately to Severely Active Polyarticular Juvenile Idiopathic Arthritis (JIA)

ENBREL is indicated for reducing signs and symptoms of moderately to severely active polyarticular juvenile idiopathic arthritis (JIA) in children ages 2 years and older.

References: 1. Parsabiv® (etelcalcetide) prescribing information, Amgen. 2. Data on file, Amgen; [Summary of Clinical Efficacy; 2015]. 3. Alexander ST, et al. Mol Pharmacol. 2015;88:853-865. 4. Data on file, Amgen; [Report R20130052, 2014]. 5. Chen P, et al. CPT Pharmacometrics Syst Pharmacol. 2016;5:484-494. 6. Sensipar® (cinacalcet) prescribing information, Amgen. 7. Ma JN, et al. J Pharmacol Exp Ther. 2011;337:275-284.
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