ENBREL Dosing for Psoriatic Arthritis

ENBREL is an injection that can fit easily into your schedule. Your doctor will tell you how often you should use ENBREL. Do NOT use ENBREL more often than prescribed.

Psoriatic arthritis dosing

The recommended dose of ENBREL for adult patients with psoriatic arthritis is typically 50 mg per week. Fifty mg can be given as one subcutaneous injection (an injection beneath the skin) using either a 50-mg/mL Enbrel® SureClick® autoinjector or 50-mg/mL single-use prefilled syringe. A 50-mg dose can also be given as two 25-mg subcutaneous injections using 25-mg/0.5 mL single-use prefilled syringes or 25-mg vials.

Do NOT miss any doses of ENBREL. Call your doctor if you miss a dose of ENBREL. Your doctor will tell you if and when you should take your missed dose.

Injection site reactions such as redness, rash, swelling, itching, or bruising may occur. These symptoms usually go away within 3 to 5 days. If you experience these reactions and they don't go away or get worse, call your doctor.

Tip: Set aside specific times every week to prepare and take your injection of ENBREL. Do NOT use ENBREL more often than prescribed.

Please see Prescribing Information, Important Safety Information, and Medication Guide for complete details about ENBREL.

Need injection help?

Watch easy-to-follow videos and see how others self-inject ENBREL.

Prescription ENBREL is taken by injection.


Psoriatic Arthritis
ENBREL is indicated for reducing signs and symptoms, keeping joint damage from getting worse, and improving physical function in patients with psoriatic arthritis. ENBREL can be used with or without methotrexate.

Supportive data
Psoriatic Arthritis
  • ENBREL was shown to be effective in about 50% of patients at 6 months. Clinical responses were apparent at the time of the first visit (4 weeks) and were maintained through 6 months of therapy.
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