When you have decided a biologic is the next step
Consider ENBREL for Patients with Moderate to Severe RA

ENBREL is indicated for reducing signs and symptoms of RA, inducing major clinical response, inhibiting the progression of structural damage, and improving physical function in patients with moderately to severely active rheumatoid arthritis. ENBREL can be initiated in combination with methotrexate (MTX) or used alone.1

Learn more about the efficacy of ENBREL from leading rheumatologists

Rapid, Sustained Efficacy of ENBREL

Review the rapid and sustained efficacy of ENBREL with KOL, Dr. Fleischmann.

Watch video

Efficacy of ENBREL Monotherapy

Review the efficacy and safety of ENBREL as monotherapy with KOL, Dr. Tesser.

Watch video

Achieving DAS 28 Clinical Remission

Review DAS 28 clinical remission results with KOL, Dr. Matsumoto.

Watch video

ENBREL demonstrated significant and sustained efficacy

Across clinical studies, ENBREL demonstrated efficacy in patients with moderate to severe RA1-4:

Improved clinical
signs and symptoms

See change from baseline in pain, morning stiffness, and CRP.

View Data

physical function

See reductions in HAQ scores.

View Data

clinical remission

See percentage of patients achieving DAS 28 clinical remission.

View Data

Inhibited progression of
joint damage

See changes in mTSS across clinical studies.

View Data

The risk of progressive structural damage is high in patients with moderate to severe RA. Structural damage may still be occurring in your RA patients despite clinical improvements with MTX alone. Adding ENBREL to MTX in moderate to severe RA has been shown to be significantly more effective than MTX alone in helping to stop progressive joint damage.
Supportive data
Moderate to Severe Rheumatoid Arthritis

In medical studies, ENBREL was shown to be clinically effective in about 2 out of 3 adults with moderate to severe RA at 3 months. ENBREL has been shown to begin working in as few as 2 weeks, and most patients who benefit will do so within 3 months. In another medical study, 55% of patients who were evaluated 5 years after beginning ENBREL therapy had no further progression of joint damage.

Psoriatic Arthritis

In a medical study, ENBREL was shown to be effective in about 50% of psoriatic arthritis patients at 6 months. Clinical responses were apparent at the time of the first visit (4 weeks) and were maintained through 6 months of therapy.

Important Safety Considerations

Introducing ENBREL Nurse Partners

Dedicated registered nurses are now available to give your patients the personal assistance
they need.

Here's how they can help
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Phil Mickelson: A PsA patient's perspective
Disease activity vs. structural progression in RA
Treating Moderately Active RA
Rapid, Sustained Efficacy of ENBREL
Improving Outcomes in Psoriatic Arthritis
Achieving Clinical Remission
Efficacy of ENBREL Monotherapy for RA
A look back at 15 years