Each single-use prefilled syringe and Enbrel® SureClick® autoinjector contains 50 mg/mL of etanercept in a single-dose syringe with a 27-gauge, 1/2-inch needle.
ENBREL multiple-use vial is supplied in a carton containing four dose trays. Each dose tray contains one 25-mg vial of etanercept, one diluent syringe (1 mL Sterile Bacteriostatic Water for Injection, USP, containing 0.9% benzyl alcohol), one 27-gauge 1/2-inch needle, one vial adapter, and one plunger. Each carton contains four "Mixing Date:" stickers.
Administration of one 50-mg prefilled syringe or one Enbrel® SureClick® autoinjector provides a dose equivalent to two 25-mg prefilled syringes or two multiple-use vials of lyophilized ENBREL, when vials are reconstituted and administered as recommended.