Efficacy in Psoriatic Arthritis

ENBREL can help reduce the signs and symptoms of psoriatic arthritis. It can also keep joint damage from getting worse. In a medical study, many psoriatic arthritis patients had3,4:

  • Less pain, swelling, and time feeling stiff in the morning
  • Clearer skin, with fewer skin symptoms

In a clinical study, ENBREL was shown to be effective in about 50% of psoriatic arthritis patients who used it at 6 months. Clinical responses were apparent at the time of the first visit (4 weeks) and were maintained through 6 months of therapy.4

Learn more about psoriatic arthritis


 
INDICATIONS

ENBREL is indicated for reducing signs and symptoms, inducing major clinical response, inhibiting the progression of structural damage, and improving physical function in patients with moderately to severely active rheumatoid arthritis. ENBREL can be initiated in combination with methotrexate (MTX) or used alone.

ENBREL is indicated for reducing signs and symptoms of moderately to severely active polyarticular juvenile idiopathic arthritis in patients ages 2 and older.

ENBREL is indicated for reducing signs and symptoms, inhibiting the progression of structural damage of active arthritis, and improving physical function in patients with psoriatic arthritis. ENBREL can be used in combination with methotrexate in patients who do not respond adequately to methotrexate alone.

ENBREL is indicated for reducing signs and symptoms in patients with active ankylosing spondylitis.

ENBREL is indicated for the treatment of adult patients (18 years or older) with chronic moderate to severe plaque psoriasis who are candidates for systemic therapy or phototherapy.

Supportive data

Moderate to Severe Plaque Psoriasis
In medical studies, nearly half of patients saw 75% skin clearance in their moderate to severe plaque psoriasis in 3 months with ENBREL. Overall, 3 out of 4 patients saw 50% skin clearance in 3 months. ENBREL can work fast; many patients saw improvement within 2 months. Your results may vary.

Psoriatic Arthritis
In a medical study, ENBREL was shown to be effective in about 50% of psoriatic arthritis patients who used it at 6 months. Clinical responses were apparent at the time of the first visit (4 weeks) and were maintained through 6 months of therapy.

Skin symptoms may precede joint symptoms by about 10 years in patients with psoriatic arthritis.1,2

1. Krueger GG. Am J Manag Care. 2002;8:S160-S170.

2. Mease PJ et al. J Am Acad Dermatol. 2005;52:1-19.

The Science of ENBREL

ENBREL blocks the activity of excess active tumor necrosis factor (TNF) to reduce the inflammation that causes plaques.

Discover the attributes
of ENBREL arrow

Shortly before the US Open, Phil Mickelson developed intense pain in his joints that progressively worsened over time.

Phil took action. He saw a doctor to learn about his options, and his doctor recommended ENBREL.

"I'm able to continue doing a number of things with my kids."